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價格 | ¥4800.00 |
品牌 | NewEast Biosciences |
產地 | 中國 武漢 |
貨號 | 26170 |
規(guī)格 | 100ul |
說明書 | 說明書下載 |
β catenin(A43V) [26170]
[100 µL]
Catalog Number: 26170 |
Gene Symbol: CTNNB1, CTNNB |
Description: Anti β catenin(A43V) Mouse Monoclonal Antibody |
Background: Beta-catenin(or β catenin) is a protein that in humans is encoded by the CTNNB1 gene. β catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer. |
Immunogen: A synthetic peptide from the internal region of β catenin which includes the mutation of A43V, human origin. |
Applications: ELISA, WB, IF, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
Host: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: |
Purity: Purified from ascites |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes β catenin(A43V), but not wild type β catenin protein from vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Western blot: |
Western blot analysis of recombinant β catenin(A43V) and wildtype proteins. Purified His-tagged β catenin(A43V) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti β catenin(A43V) mouse monoclonal antibody (Cat. #26170). |
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